|
Symbol Name ID |
Glis3
GLIS family zinc finger 3 MGI:2444289 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Diabetes mellitus |
Pancreatic hypoplasia |
Pancreatic cysts |
Decreased circulating T4 concentration |
Elevated circulating thyroid-stimulating hormone concentration |
Congenital hypothyroidism |
| Disease(s) Associated with GLIS3 | ||||||
| neonatal diabetes mellitus with congenital hypothyroidism |
| Mouse Phenotypes | endocrine/exocrine gland phenotype |
abnormal pancreatic islet morphology |
decreased pancreatic alpha cell number |
absent pancreatic alpha cells |
decreased pancreatic beta cell number |
absent pancreatic beta cells |
decreased pancreatic delta cell number |
decreased pancreatic epsilon cell number |
small pancreatic islets |
disorganized pancreatic islets |
decreased insulin secretion |
decreased activity of thyroid gland |
abnormal pancreas physiology |
|
| Availability | Mouse Genotype | |||||||||||||
| Glis3tm1.2Chan/Glis3tm1.2Chan | * | |||||||||||||
| Glis3tm1Hiha/Glis3tm1Hiha | ||||||||||||||
| Glis3tm1.2Chan/Glis3+ | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools